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1

Technology trends in antibody purification

Journal:

Journal of Chromatography A

Year:

2012

Language:

english

File:

PDF, 536 KB

english, 2012

2

Monoclonal antibody purification with hydroxyapatite

Journal:

New Biotechnology

Year:

2009

Language:

english

File:

PDF, 352 KB

english, 2009

3

Allantoin as a solid phase adsorbent for removing endotoxins

Vagenende, Vincent, Ching, Tim-Jang, Chua, Rui-Jing, Gagnon, Pete

Journal:

Journal of Chromatography A

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

4

Histone-dependent IgG conservation in octanoic acid precipitation and its mechanism

Chen, Quan, Toh, Phyllicia, Sun, Yue, Latiff, Sarah Maria Abdul, Hoi, Aina, Xian, Mo, Zhang, Haibo, Nian, Rui, Zhang, Wei, Gagnon, Pete

Journal:

Applied Microbiology and Biotechnology

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

5

Purification of monomeric mAb from associated aggregates using selective desorption chromatography in hydroxyapatite systems

Christopher J. Morrison, Pete Gagnon, Steven M. Cramer

Journal:

Biotechnology and Bioengineering

Year:

2011

Language:

english

File:

PDF, 2.33 MB

english, 2011

6

Cooperative multimodal retention of IgG, fragments, and aggregates on hydroxyapatite

Pete Gagnon, Chia-Wei Cheung, Paul J. Yazaki

Journal:

Journal of Separation Science

Year:

2009

Language:

english

File:

PDF, 273 KB

english, 2009

7

PEG enhances viral clearance on ceramic hydroxyapatite

Mark A. Snyder, Paul Ng, Heather Mekosh, Pete Gagnon

Journal:

Journal of Separation Science

Year:

2009

Language:

english

File:

PDF, 80 KB

english, 2009

8

Method for obtaining unique selectivities in ion-exchange chromatography by addition of organic polymers to the mobile phase

Pete Gagnon, Bill Godfrey, Don Ladd

Journal:

Journal of Chromatography A

Year:

1996

Language:

english

File:

PDF, 318 KB

english, 1996

9

Dissociation and fractionation of heavy and light chains from IgG monoclonal antibodies

Pete Gagnon, George Rodriquez, Simin Zaidi

Journal:

Journal of Chromatography A

Year:

2011

Language:

english

File:

PDF, 184 KB

english, 2011

10

Chromatographic behavior of IgM:DNA complexes

Pete Gagnon, Frank Hensel, Soon Lee, Simin Zaidi

Journal:

Journal of Chromatography A

Year:

2011

Language:

english

File:

PDF, 446 KB

english, 2011

11

An adaptation of hydrophobic interaction chromatography for estimation of protein solubility optima

Pete Gagnon, Terry Mayes, Åke Danielsson

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1997

Language:

english

File:

PDF, 107 KB

english, 1997

12

Unique selectivity windows using selective displacers/eluents and mobile phase modifiers on hydroxyapatite

Christopher J. Morrison, Pete Gagnon, Steven M. Cramer

Journal:

Journal of Chromatography A

Year:

2010

Language:

english

File:

PDF, 1.55 MB

english, 2010

13

Mechanistic model for adsorption of immunoglobulin on hydroxyapatite

Paul K. Ng, Jie He, Pete Gagnon

Journal:

Journal of Chromatography A

Year:

2007

Language:

english

File:

PDF, 269 KB

english, 2007

14

Improved antibody aggregate removal by hydroxyapatite chromatography in the presence of polyethylene glycol

Journal:

Journal of Immunological Methods

Year:

2008

Language:

english

File:

PDF, 608 KB

english, 2008

15

Reverse calcium affinity purification of Fab with calcium derivatized hydroxyapatite

Pete Gagnon, Chia-Wei Cheung, Paul J. Yazaki

Journal:

Journal of Immunological Methods

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

16

The effects of hitchhiker antigens co-eluting with affinity-purified research antibodies

Lilly Mechetner, Radhika Sood, Van Nguyen, Pete Gagnon, Missag H. Parseghian

Journal:

Journal of Chromatography B

Year:

2011

Language:

english

File:

PDF, 1.60 MB

english, 2011

17

Principles and applications of steric exclusion chromatography

Lee, Jeremy, Gan, Hui Theng, Latiff, Sarah Maria Abdul, Chuah, Cindy, Lee, Wan Yee, Yang, Yuan-Sheng, Loo, Bernard, Ng, Say Kong, Gagnon, Pete

Journal:

Journal of Chromatography A

Year:

2012

Language:

english

File:

PDF, 964 KB

english, 2012

18

Void exclusion of antibodies by grafted-ligand porous particle anion exchangers

Nian, Rui, Chuah, Cindy, Lee, Jeremy, Gan, Hui Theng, Latiff, Sarah Maria Abdul, Lee, Wan Yee, Vagenende, Vincent, Yang, Yuan-Sheng, Gagnon, Pete

Journal:

Journal of Chromatography A

Year:

2013

Language:

english

File:

PDF, 728 KB

english, 2013

19

Characterization and removal of aggregates formed by nonspecific interaction of IgM monoclonal antibodies with chromatin catabolites during cell culture production

Gan, Hui Theng, Lee, Jeremy, Latiff, Sarah Maria Abdul, Chuah, Cindy, Toh, Phyllicia, Lee, Wan Yee, Gagnon, Pete

Journal:

Journal of Chromatography A

Year:

2013

Language:

english

File:

PDF, 1.13 MB

english, 2013

20

Amide-Mediated Hydrogen Bonding at Organic Crystal/Water Interfaces Enables Selective Endotoxin Binding with Picomolar Affinity

Vagenende, Vincent, Ching, Tim-Jang, Chua, Rui-Jing, Thirumoorthi, Navanita, Gagnon, Pete

Journal:

ACS Applied Materials & Interfaces

Year:

2013

Language:

english

File:

PDF, 3.00 MB

english, 2013

21

Nonspecific interactions of chromatin with immunoglobulin G and protein A, and their impact on purification performance

Gagnon, Pete, Nian, Rui, Lee, Jeremy, Tan, Lihan, Latiff, Sarah Maria Abdul, Lim, Chiew Ling, Chuah, Cindy, Bi, Xuezhi, Yang, Yuansheng, Zhang, Wei, Gan, Hui Theng

Journal:

Journal of Chromatography A

Year:

2014

Language:

english

File:

PDF, 1.54 MB

english, 2014

22

High productivity purification of immunoglobulin G monoclonal antibodies on starch-coated magnetic nanoparticles by steric exclusion of polyethylene glycol

Gagnon, Pete, Toh, Phyllicia, Lee, Jeremy

Journal:

Journal of Chromatography A

Year:

2014

Language:

english

File:

PDF, 1.42 MB

english, 2014

23

Self-assembly of lipopolysaccharide layers on allantoin crystals

Vagenende, Vincent, Ching, Tim-Jang, Chua, Rui-Jing, Jiang, Qiu Zhen, Gagnon, Pete

Journal:

Colloids and Surfaces B: Biointerfaces

Year:

2014

Language:

english

File:

PDF, 1.59 MB

english, 2014

24

Chromatin-mediated depression of fractionation performance on electronegative multimodal chromatography media, its prevention, and ramifications for purification of immunoglobulin G

Gagnon, Pete, Nian, Rui, Tan, Lihan, Cheong, Jason, Yeo, Veronica, Yang, Yuansheng, Gan, Hui Theng

Journal:

Journal of Chromatography A

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

25

Void Exclusion Biomanufacturing Method

Journal:

Genetic Engineering & Biotechnology News

Year:

2014

Language:

english

File:

PDF, 155 KB

english, 2014

26

Steric Exclusion Chromatography

Journal:

Genetic Engineering & Biotechnology News

Year:

2013

Language:

english

File:

PDF, 149 KB

english, 2013

27

Characterization of DNA in cell culture supernatant by fluorescence-detection size-exclusion chromatography

Tan, Lihan, Yeo, Veronica, Yang, Yuansheng, Gagnon, Pete

Journal:

Analytical and Bioanalytical Chemistry

Year:

2015

Language:

english

File:

PDF, 2.62 MB

english, 2015

28

Transient conformational modification of immunoglobulin G during purification by protein A affinity chromatography

Gagnon, Pete, Nian, Rui, Leong, Denise, Hoi, Aina

Journal:

Journal of Chromatography A

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

29

Non-immunospecific association of immunoglobulin G with chromatin during elution from protein A inflates host contamination, aggregate content, and antibody loss

Gagnon, Pete, Nian, Rui, Yang, Yuansheng, Yang, Qiaohui, Lim, Chiew Ling

Journal:

Journal of Chromatography A

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

30

Immunoglobulins M survive Low-pH conditions used for virus inactivation and for elution from bioaffinity columns

Mueller, Monika, Wan, Corrine, Hoi, Kong Meng, Kim, Do Yun, Gan, Hui Theng, Bardor, Muriel, Gagnon, Pete

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 251 KB

english, 2013

31

Advance chromatin extraction improves capture performance of protein A affinity chromatography

Nian, Rui, Zhang, Wei, Tan, Lihan, Lee, Jeremy, Bi, Xeuzhi, Yang, Yuansheng, Gan, Hui Theng, Gagnon, Pete

Journal:

Journal of Chromatography A

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

32

Conformational plasticity of IgG during protein A affinity chromatography

Gagnon, Pete, Nian, Rui

Journal:

Journal of Chromatography A

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

33

Advance chromatin extraction enhances performance and productivity of cation exchange chromatography-based capture of Immunoglobulin G monoclonal antibodies

Nian, Rui, Gagnon, Pete

Journal:

Journal of Chromatography A

Year:

2016

Language:

english

File:

PDF, 213 KB

english, 2016

34

Solvent Modulation of Column Chromatography

Arakawa, Tsutomu, Kita, Yoshiko, Ejima, Daisuke, Gagnon, Pete

Journal:

Protein & Peptide Letters

Year:

2008

Language:

english

File:

PDF, 242 KB

english, 2008

35

IgG Aggregate Removal by Charged-Hydrophobic Mixed Mode Chromatography

Journal:

Current Pharmaceutical Biotechnology

Year:

2009

Language:

english

File:

PDF, 256 KB

english, 2009

36

Antibody Aggregate Removal by Hydroxyapatite Chromatography

Gagnon, Pete, Beam, Kevin

Journal:

Current Pharmaceutical Biotechnology

Year:

2009

Language:

english

File:

PDF, 279 KB

english, 2009

37

A simple and efficient purification platform for monoclonal antibody production based on chromatin-directed cell culture clarification integrated with precipitation and void-exclusion anion exchange chromatography

Chen, Quan, Abdul Latiff, Sarah Maria, Toh, Phyllicia, Peng, Xinying, Hoi, Aina, Xian, Mo, Zhang, Haibo, Nian, Rui, Zhang, Wei, Gagnon, Pete

Journal:

Journal of Biotechnology

Year:

2016

Language:

english

File:

PDF, 1.73 MB

english, 2016

38

Excluded Cosolvent in Chromatography

Arakawa, Tsutomu, Gagnon, Pete

Journal:

Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 889 KB

english, 2018

39

Editorial [Hot Topic: Aggregation Detection and Removal Biopharmaceutical Proteins (Guest Editors: Pete Gagnon & Tsutomu Arakawa)]

Gagnon, Pete, Arakawa, Tsutomu

Journal:

Current Pharmaceutical Biotechnology

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

40

Accelerating AAV to the Clinic with Purification Improvements

Journal:

Genetic Engineering & Biotechnology News

Year:

2019

File:

PDF, 368 KB

2019